| Hepatitis B Clinical Status |
| Bold signifies distinctive and required results to determine each status Others state result that is consistent with status but not a required test. Empty cells mean that any result is consistent with status. |
| Test |
Chronic |
Carrier |
Resolved |
Vaccinated |
| HBsAb |
Negative |
|
Positive |
Positive |
| HBsAg |
Positive > 6 mo |
Positive > 6 mo |
Negative |
Negative |
| LFT |
Persistent or intermittent abnormality |
Always normal |
Normal |
Normal |
| DNA |
Present |
Absent |
Absent |
Absent |
| HBeAg |
|
|
Negative |
Negative |
| HBeAb |
|
|
|
Negative |
| HBcAb |
|
|
Positive |
Negative |
| Biopsy |
> 3 |
0 - 3 (necroinflammatory score) |
| Viral hepatitis biopsy classification |
| Fibrosis stage |
Fibrosis description |
Necrosis/inflammation |
Inflammation description |
| F0 |
No fibrosis |
Grade 0 - 2 |
Zero or mild lobular or nodular necrosis AND |
| F1 - F2 |
Periportal fibrous expansion |
|
zero or mild inflammation in < 1/3 of portal tracts |
| F3 |
Bridging fibrosis, porto-portal, porto-central fibrosis |
Grade 3 - 4 |
Moderate or marked lobular or nodular necrosis AND/OR moderate or marked inflammation in 1/3 or more of portal tracts |
| F4 |
Cirrhosis |
|
|
